We obtained a Proof of Concept (POC) grant from the European Research Council (ERC) to develop an innovative therapy targeting obesity-related liver cancer

The REPRO-PTP project targets tyrosine phosphatase proteins (PTP), a promising but still little therapeutically explored class of enzymes regulating cell signaling. The Signal Transduction and Metabolism Laboratory directed by Pr. Esteban Gurzov identified PTPRK, a receptor PTP that regulates glycolysis and lipogenesis, as a key player in obesity-related HCC. Based on cutting-edge research and proprietary inhibitors, REPRO-PTP aims to develop PTPRK inhibitors with unparalleled efficacy.

More information here.

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Congratulations to Dr Valerie Vandenbempt, Dr Wadsen St Pierre Wijckmans, Dr Israel Pérez Chávez, and Dr Ao Li

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Our latest paper is online in Nature Communications!